Next Generation Single-Molecule Biophysics
CHIRLMIN JOO LAB
Using next-generation single-molecule fluorescence techniques, we investigate how small regulatory RNA mediates gene silencing (RNA interference) and anti-viral defense (CRISPR immunity and beyond). We develop single-molecule protein sequencing techniques for advanced proteomics analysis. We organized conferences in 2017, 2019, 2022 .
KEY PUBLICATIONS
Severins, Bastiaanssen, Kim, et al, C. Joo "Single-molecule structural and kinetic studies across sequence space" Science (2024)
Bastiaanssen, Kim et al "RNA-guided RNA silencing by an Asgard archaeal Argonaute" Nature Communications (2024)
Filius et al, "Full-length single-molecule protein fingerprinting" Nature Nanotechnology (2024)
Alfaro et al, "The emerging landscape of single-molecule protein sequencing technologies" Nature Methods (2021)
Kim, Loeff et al "Selective loading and processing of prespacers for precise CRISPR adaptation" Nature (2020) (animation)
LAB NEWS
Oct 2024 Chirlmin gives a talk in Single-Molecule Sensors and NanoSystems International Conference
Sep 2024 Sungchul becomes an assistant professor in POSTECH, Korea
Aug 2024 Ivo•Carolien•Sung Hyun's paper published in Science (TU Delft, Delta, GenomeWeb, NL, NL, BE, Korea, Ewha)
Jul 2024 Carolien defends her PhD thesis
Jul 2024 Bhagyashree•Carlos•Sung Hyun's paper published in Nano Letters
Jul 2024 Sohyun joins the Ewha lab for her internship project
Jul 2024 KyungLim joins the Ewha lab for her internship project
Jul 2024 Carolien•Kijun's paper published in Nature Communications
Jun 2024 Convergence consortium paper published in PLoS Climate
Jun 2024 Carolien gives a talk in Physics of Life
May 2024 Mike gives a talk in Norwegian Symposium on Proteomics
May 2024 Ivo defends his PhD thesis
Mar 2024 Carlos becomes Faculty of Impact fellow (NWO)
Feb 2024 Mike•Raman•Carlos's work published in Nature Nanotechnology (TU Delft, delta, genengnews, phys, newbeezer, myscience)
Feb 2024 Marianne joins our lab for her internship project
Feb 2024 Senne joins our lab for his bachelor project
Feb 2024 Carolien gives a talk in BPS Meeting
Jan 2024 We are awarded ERC Proof of Concept (TU Delft)
Jan 2024 Koushik gives a talk in Single-Molecule Biophysics Les Houches
See also news in 2011- 2023